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The most popular hotels in Departamento de Santa Cruz

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Departamento de Santa Cruz Hotels for Your Next Holiday

Why Tourists Visit Departamento de Santa Cruz

  • * Explore the ancient ruins at El Fuerte de Samaipata.
  • * Visit the butterfly sanctuary and pools at Biocentro Guembe.
  • * Go trekking or bird-watching in Amboró National Park.
  • * Stroll around the iconic Plaza 24 de Septiembre in Santa Cruz city.
  • * Enjoy a refreshing boat ride along the Espejillos waterfalls.

Departamento de Santa Cruz boasts over 200 hotels, ranging from budget-friendly options in Santa Cruz city to boutique escapes in Samaipata and luxury stays in Equipetrol. Average nightly rates for 3-star hotels range between $35-$80, while 5-star hotels cost $120-$250 on average. A standout among recently opened accommodations is the Marriott Santa Cruz de la Sierra Hotel, featuring modern amenities and situated in the city's trendiest area.

Departamento de Santa Cruz, Bolivia's largest region, is known for its vibrant city life, sprawling Amazonian parks, and breathtaking Andean foothills, offering travelers an eclectic mix of nature and culture.

Tourists flock here to visit marquee attractions like Biocentro Guembe, Amboró National Park, and Samaipata's UNESCO-listed El Fuerte archaeological site.

With a blend of cosmopolitan appeal and natural beauty, this region provides countless experiences, from wildlife spotting to sampling delicious Santa Cruz cuisine.

Departamento de Santa Cruz Tips You Must Know

* Book your hotel 3-4 months in advance if visiting between May and September, the dry season and peak travel period.

* Opt for hotels in Equipetrol if you want a seamless mix of nightlife, dining, and upscale shopping.

* Public transportation is limited-rent a car or use ride-hailing apps for convenience.

* Look for accommodations with air conditioning, as temperatures often exceed 85°F (29°C).

* Always carry cash for smaller hotels or purchases in remote areas, as card payments are not universally accepted.

Santa Cruz de la Sierra

Santa Cruz de la Sierra, the capital of the department, combines modern vibrance with historical charm. Its Plaza 24 de Septiembre is surrounded by colonial buildings and the iconic Metropolitan Cathedral. The city also hosts one of South America's largest Carnaval celebrations.

Browse the best hotels in Santa Cruz de la Sierra and stay close to its iconic landmarks and exciting events.

Samaipata

Samaipata, nestled in the foothills of the Andes, is home to the UNESCO-listed El Fuerte archaeological site. The town offers a gateway to Amboró National Park, known for its rich biodiversity. Quaint streets and artisan markets create a relaxed, bohemian vibe.

Explore charming hotels in Samaipata and enjoy the serene mountain atmosphere.

San José de Chiquitos

San José de Chiquitos showcases its Jesuit past through its beautifully restored 18th-century mission church, a UNESCO World Heritage Site. The town lies on the Ruta de las Misiones, preserving Bolivia's colonial-era architecture. Travelers often rave about the scenic nature trails nearby.

Discover cozy hotels in San José de Chiquitos while exploring its stunning Jesuit heritage.

Cotoca

Cotoca attracts visitors for its famous Basilica of the Virgin of Cotoca, a major pilgrimage site in Bolivia. Additionally, its vibrant pottery markets highlight the town's artisanal traditions. Cotoca's bustling food stalls are perfect for sampling local delicacies like tamales and humintas.

Find great-value hotels in Cotoca close to its cultural and culinary spots.

Concepción

Concepción is celebrated for its Jesuit Mission complex, a UNESCO World Heritage Site with breathtaking murals and wooden carvings. The town also hosts the International Baroque Music Festival biennially. Nearby lagoons and forests provide excellent opportunities for eco-tourism and bird-watching.

Check out peaceful hotels in Concepción that pair comfort with cultural exploration.

Central Charm: Hotels in the Heart of Action

Find more exceptional Central hotels in Santa Cruz de la Sierra today.

Hotel Name
Description
#
Price per night

Cosmopolitano Hotel Boutique

Central District

  • Plaza 24 de Septiembre (0.8 km)
  • Sacred Art Museum (0.6 km)
  • Arenal Park (1 km)

This boutique gem is housed in a modernist-inspired building, blending contemporary art with lush courtyards. Its intimate size provides personalized service that guests rave about.

  • Artistic interior design

  • Tranquil garden

  • Excellent central location

$80-$120/night

Chairu Eco Hotel

Santa Cruz de la Sierra

  • Ventura Mall (1.5 km)
  • Hard Rock Cafe (1.8 km)
  • Las Brisas Mall (2 km)

An eco-conscious hotel designed with sustainability in mind, featuring solar energy and locally sourced materials. Guests love the rooftop terrace with panoramic city views.

  • Eco-friendly practices

  • Modern rooftop terrace

  • Friendly service

$70-$100/night

Hotel Camino Real

Equipetrol

  • Ventura Mall (0.5 km)
  • Santa Cruz Zoo (2.5 km)
  • Pirai River Walk (2 km)

This upscale hotel is famed for its lagoon-style outdoor pool and tropical garden. Its acclaimed spa offerings make it a top choice for relaxation.

  • Lagoon pool

  • Luxury spa facilities

  • Prime location

$120-$180/night

Indulge Yourself: Top Luxury Hotels

Indulge in the best Luxury hotels in Santa Cruz de la Sierra for an unforgettable experience.

Hotel Name
Description
#
Price per night

Tryp By Wyndham Santa Cruz

Santa Cruz de la Sierra

  • Ventura Mall (2 km)
  • Arenal Park (3 km)
  • Plaza 24 de Septiembre (4 km)

This hotel features Bolivia's first rooftop infinity pool with 360-degree city views. Its gourmet restaurant attracts locals and guests alike for fine dining.

  • Infinity pool

  • Gourmet dining

  • Stylish design

$150-$250/night

Sun Hotel

Viru Viru District

  • Viru Viru Airport (2 km)
  • Biocentro Guembe (10 km)
  • Santa Cruz city center (15 km)

Conveniently situated near the airport, this hotel offers serene landscapes and an expansive pool. It's a favorite for business travelers and transit guests.

  • Close to airport

  • Large swimming pool

  • Quiet surroundings

$120-$200/night

Los Tajibos, Santa Cruz De La Sierra, A Tribute Portfolio Hotel

Equipetrol

  • Ventura Mall (1 km)
  • Santa Cruz Zoo (1.5 km)
  • Arenal Park (4 km)

This iconic hotel is known for hosting high-profile events and Bolivia's most elaborate tropical gardens. The pool area feels like a luxury oasis.

  • Lush gardens

  • Event hosting

  • Luxury amenities

$180-$300/night

Boutique Delight: Intimate Stays

Discover more stylish Boutique hotels in Santa Cruz de la Sierra crafted for unique stays.

Hotel Name
Description
#
Price per night

Senses Hotel Boutique Plaza

Central District

  • Santa Cruz Cathedral (0.1 km)
  • Sacred Art Museum (0.2 km)
  • Arenal Park (0.6 km)

Located right on Plaza 24 de Septiembre, this hotel offers views of Santa Cruz Cathedral and vibrant city energy. Each room is uniquely decorated for a bespoke experience.

  • Unique decor

  • Central location

  • Cultural landmarks nearby

$90-$160/night

Alfonsina Hotel Boutique

Equipetrol

  • Ventura Mall (1.8 km)
  • Santa Cruz Zoo (2.2 km)
  • Pirai River Walk (2.5 km)

A modern boutique hotel that prioritizes guest wellness with vegan meal options and yoga classes. Its interior is inspired by local art and minimalism.

  • Vegan-friendly

  • Art-inspired interiors

  • Yoga facilities

$110-$170/night

Hotel Senses Centro

Santa Cruz de la Sierra

  • Plaza 24 de Septiembre (0.5 km)
  • Arenal Park (0.9 km)
  • Sacred Art Museum (0.4 km)

This hotel combines chic interiors with a rooftop pool offering panoramic views of the city. Its proximity to nightlife spots makes it popular among young travelers.

  • Rooftop pool

  • Chic design

  • Central nightlife access

$80-$150/night

Family Time: Kid-Friendly Hotels

Explore welcoming Family Friendly hotels in Santa Cruz de la Sierra for your next family adventure.

Hotel Name
Description
#
Price per night

Hotel Plaza Center

Santa Cruz de la Sierra

  • Arenal Park (0.5 km)
  • Santa Cruz Zoo (2 km)
  • Plaza 24 de Septiembre (1.5 km)

This hotel features spacious family suites and a dedicated kids play area. It's minutes away from family-friendly attractions like Arenal Park.

  • Kid-friendly facilities

  • Family suites

  • Central location

$70-$120/night

Yvy Casa Hotel

Samaipata

  • El Fuerte de Samaipata (8 km)
  • Amboró National Park (15 km)
  • Samaipata central square (0.8 km)

A cozy family-run property offering guided tours to nearby forests and attractions. Guests praise the homemade breakfasts featuring local ingredients.

  • Family-run hospitality

  • Guided tours

  • Hearty breakfasts

$60-$90/night

Hostel Serena

Santa Cruz de la Sierra

  • Hard Rock Cafe (2 km)
  • Santa Cruz Zoo (3 km)
  • Las Brisas Mall (3.5 km)

Budget-friendly and kid-friendly hosting, complete with shared gardens and play zones. The on-site café serves dishes tailored to little ones.

  • Affordable rates

  • Family-friendly

  • Play zones available

$30-$60/night

Relaxation Undercover: Hotels With Indoor Pools

Discover relaxing Hotels with indoor pool in Santa Cruz de la Sierra for a leisurely escape.

Hotel Name
Description
#
Price per night

Departamentos En Edificio Acrebol Santa Cruz

Santa Cruz de la Sierra

  • Ventura Mall (2 km)
  • Santa Cruz Zoo (2.5 km)
  • Pirai River Walk (3 km)

This apartment-style hotel boasts a rare indoor heated pool for year-round enjoyment. Convenient for longer stays, it offers fully equipped kitchens in every unit.

  • Indoor heated pool

  • Apartment amenities

  • Peaceful environment

$80-$140/night

Metta One

Santa Cruz de la Sierra

  • Arenal Park (1 km)
  • Plaza 24 de Septiembre (1.8 km)
  • Las Brisas Mall (1.5 km)

With sleek interiors and an elegant indoor pool deck, this hotel blends relaxation with urbanity. Smartly designed for business visitors and weekend getaways.

  • Stylish design

  • Indoor pool

  • Business-friendly

$100-$200/night

Hermoso Apartamento

Equipetrol

  • Ventura Mall (0.8 km)
  • Santa Cruz Zoo (1.6 km)
  • Pirai River Walk (1.7 km)

This unique aparthotel combines luxury design with a private indoor pool. Ideal for travelers seeking privacy alongside elegant comforts.

  • Private indoor pool

  • Stylish interiors

  • Luxury comfort

$120-$180/night

Frequently asked question

What are the best areas to stay in Departamento de Santa Cruz?

The best areas to stay include Equipetrol for upscale hotels and dining, Samaipata for nature and boutique stays, and Santa Cruz city center for budget-friendly options close to popular attractions.

Are there family-friendly hotels available in Santa Cruz?

Yes, family-friendly hotels like Hotel Camino Real offer kid-friendly amenities such as pools and family rooms.

What is the average cost of hotels in Departamento de Santa Cruz?

Budget hotels range from $30-$50 per night, mid-range options typically cost $70-$120, and luxury stays can go up to $200 or more per night.

Are there any hotels near Biocentro Guembe?

Yes, hotels such as Buganvillas Hotel Suites & Spa are located a short distance from Biocentro Guembe, offering easy access to the attraction.

Can I find boutique hotels in Departamento de Santa Cruz?

Boutique hotels like El Pueblito Resort in Samaipata offer charming and personalized service in picturesque surroundings.

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